Francis Charhon studied medicine and specialized in anesthesia. After a career in the hospital environment, he joined Médecins Sans Frontières (Doctors without borders) in 1980, at first as president. In 1982, he was appointed managing director of the association and remained in that role until 1991. In 1992, Charhon began to undertake the same responsibilities for Fondation de France. He is also vice president of France Générosités (Union of the charity organizations). President of the French Foundation Centre from 2002 to June 2015, and honorary president since July 2015. board director of the French chamber of social economy since 2014. Charhon is the member of the monitoring committee of endowment at the legal affairs counsel of the French economic and financial ministries since 2014. Charhon is the board director of the NGO Convergences, since 2015. He is the member of the French Economic, Social and Environmental Council from 2010 to 2015 and member of Conseil National du Développement et de la Solidarité Internationale (CNDSI) from 2014 to 2015.